Product Description
Contains:
Each mL Contains Artemether 20mg/40mg/60mg/80mg
Package:
40mg per ampoule *6 in box,
60mg per ampoule *6 in box,
80mg per ampoule *6 in box
Indications
Alternative to injectable artesunate (when it is not available) in the:
Treatment of severe malaria
Initial treatment of uncomplicated malaria, when persistent vomiting precludes oral therapy
Forms and strengths, route of administration
80 mg in 1 ml ampoule (80 mg/ml), oily solution for IM injection. NEVER ADMINISTER BY IV ROUTE.
When the dose required is less than 1 ml, use a 1 ml syringe graduated in 0.01 ml.
Dosage and duration
- Child and adult:
3.2 mg/kg by IM injection on the first day followed by 1.6 mg/kg once daily
| Weight | 80 mg ampoule | |
|---|---|---|
| Loading dose | Maintenance dose | |
3-4 kg | 0.2 ml | 0.1 ml |
5-6 kg | 0.3 ml | 0.15 ml |
7-9 kg | 0.4 ml | 0.2 ml |
10-14 kg | 0.6 ml | 0.3 ml |
15-19 kg | 0.8 ml | 0.4 ml |
20-29 kg | 1.2 ml | 0.6 ml |
30-39 kg | 1.6 ml | 0.8 ml |
40-49 kg | 2 ml | 1 ml |
50-59 kg | 2.5 ml | 1.2 ml |
- Treat parenterally for at least 24 hours (2 doses), then, if the patient can tolerate the oral route, change to a complete 3-day course of an artemisinin-based combination. If not, continue parenteral treatment once daily until the patient can change to oral route (without exceeding 7 days of parenteral treatment).
Contra-indications, adverse effects, precautions
May cause: gastrointestinal disturbances, dizziness.
Pregnancy: no contra-indication
Breast-feeding: no contra-indication
Storage
Below 25 °C
